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What is Zoloft Generic Medicine?

Zoloft is one of the most popular antidepressants of our time, which earned its quadrupeds due to its excellent properties in the treatment of depression, compulsive rastrojstvo psychoneurotic, depressed.Generic Zoloft often used in long-term therapy, but also effective in short-time use in the process of correcting the mental state of the person.

Mechanism of Action of the Generic Zoloft

Drug For Treatment Depression Zoloft is medication, specific monoamine neurotransmitter uptake matter, enhances its effects, has very little result on the uptake of monoamine neurotransmitter and Intropin, in therapeutic doses, inhibits the uptake of monoamine neurotransmitter in human platelets. Inhibition of monoamine neurotransmitter uptake activity will increase serotonergic transmission, that ends up in resultant inhibition adrenergic activity within the locus ceruleus (locus ceruleus). Zoloft inhibits the initiation of monoamine neurotransmitter neurons within the weld space (middle line of the medulla oblongata), that ends up in associate degree initial increase in activity of light-blue area, followed by slashed activity of postsynaptic beta-adrenergic receptors and presynaptic alpha2-adrenergic receptors. It doesn't cause drug dependence has not psihoostimuliruyuschego, sedation, anticholinergic and m-cardiotoxic action doesn't alter the content activity. By selective inhibition of monoamine neurotransmitter doesn't increase the activity of the sympathetic systema nervosum. it's no affinity for M-choline, monoamine neurotransmitter (5-HT1A, 5-HT1B, 5-HT2), dopamine, adrenergic, histamine, or GABA-benzodiazepine receptors, didn't inhibit MAO. not like antidepressant drug antidepressants within the treatment of depression or psychoneurotic compulsive disorders (obsessive-compulsive disorder) doesn't increase weight. The initial result develops inside seven days, full - when 2-4 weeks.

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Generic Zoloft Side Effects

Allergic reactions, hemorrhage (including nose), palpitations, dry mouth, loss of appetence. seldom - raised appetence (perhaps as a consequence of eliminating depression), nausea, vomiting, unstable stool, diarrhea, abdomen cramps or abdominal pain, bloating or pain, weight loss, headache, dizziness, insomnia, somnolence, tremor, movement disorders (extrapyramidal symptoms, changes in gait), akathisia, seizures, paresthesias, symptoms of depression, hallucinations, aggressiveness, agitation, anxiety, psychosis, skin flushing or "tides" of blood to the face, visual disturbances (including blurred vision), yawning, sweating, sexual violation operate (delayed ejaculation, bated efficiency and / or physical attraction, anorgasmia), pain, galactorrhea, hypomania, mania, symptom (syndrome of inappropriate secretion of medicament hormone), hyperprolactinemia syndrome "cancel", erythema, efflorescence and zud. Cialis Canadian Pharmacy Online Overdose. Symptoms: anxiety, somnolence, graph changes, mydriasis, nausea, vomiting, arrhythmia. Treatment: the supply of a standard airway (oxygenation and ventilation), lavage, unconditioned reflex medicine, atomic number 6 with sorbitol. Necessary to regulate the functions of the center and liver. Ineffective forced symptom, dialysis, hemoperfusion and blood transfusion (given the massive volume of distribution).

Dosage and Administration To Effective Treat Depression

Inside, 50 mg, one dose in the morning or evening, with or without food. If no effect may be gradual (for several weeks) increasing the dose up to 200 mg / day (50 mg / week). Some clinicians recommend appoint first dose of 25 mg / day for 1-2 days. Panic disorder: initial dose - 25 mg / day, increasing to 50 mg / day for 1 week. When conducting long-term maintenance therapy is prescribed in the lowest effective dose, which subsequently change depending on the effect. Obsessive-compulsive disorder: In children and adolescents 13-17 years of the initial dose - 50 mg / day in children 6-12 years of the initial dose - 25 mg / day, followed by an increase within 1 week to 50 mg / day. With little effect dose can be increased stepwise by 50 mg / day to 200 mg / day, with an interval of at least 1 week. In elderly patients the initial dose - 25 mg / day (morning or evening) followed by a gradual increase.